Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity
Assessment of a 3D neural spheroid model to detect pharmaceutical-induced neurotoxicity Read more
Comparative assessment of Ca2+ oscillations in 2- and 3-dimensional hiPSC derived and isolated cortical neuronal networks
In 2023, Merck, Sanofi, and Fujifilm Cellular Dynamics collaborated as part of the IMI2 NeuroDerisk initiative to perform a comparative
Advances in 3D neuronal microphysiological systems: towards a functional nervous system on a chip
January 12, 2021 AxoSim published a review paper with Springer Nature’s In Vitro Cellular & Developmental Biology – Animal on
Fabrication and Characterization of 3D Printed, 3D Microelectrode Arrays for Interfacing with a Peripheral Nerve-on-a-Chip
December 10, 2020 We present a nontraditional fabrication technique for the realization of three-dimensional (3D) microelectrode arrays (MEAs) capable of
Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model
February 21. 2020 Selective serotonin reuptake inhibitors (SSRIs) are frequently used to treat depression during pregnancy. Various concerns have been
Modeling chemotherapy-induced peripheral neuropathy using a nerve-on-a-chip microphysiological system
July 15, 2020 Organ-on-a-chip devices that mimic in vivo physiology have the potential to identify effects of chemical and drug exposure in
Rotenone exerts developmental neurotoxicity in a human brain spheroid model
September 1, 2018 Growing concern suggests that some chemicals exert (developmental) neurotoxicity (DNT and NT) and are linked to the
Rotenone exerts developmental neurotoxicity in a human brain spheroid model Read more
Microengineered peripheral nerve-on-a-chip for preclinical physiological testing
March 27, 2015 The use of advanced in vitro testing is a powerful tool to develop predictive cellular assays suitable
Microengineered peripheral nerve-on-a-chip for preclinical physiological testing Read more
A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity
July 16, 2018 Human in vitro models of brain neurophysiology are needed to investigate molecular and cellular mechanisms associated with